The specialists of “edited” DNA of the cells of the immune system. They then successfully engrafted in the body of a person infected with HIV and have begun to actively fight the infection. No side effects when it was observed, informs Molecular Therapy.
All this allowed to improve HIV immunotherapy. Experts say that any harm the patient’s immune cells do not carry.
The immunodeficiency virus in the human body goes through protein compounds which it is covered. The structure is constantly changing, which is why the immune system produces each time a new set of antibodies.
Usually wins HIV, because changes faster than healthy cells can fight. That is why scientists cannot create a vaccine through three or four years it becomes useless. And this time is spent in a constant struggle of the body that weakens due to the ongoing struggle.
However, as it turned out, the problem is solved. Experts have learned to “train” immune cells. Now they are able to produce antibodies much earlier – before the onset of exhaustion of the immune system. In 2017, Penn biologists conducted the first experiment modification of DNA so that they increasingly began to produce antibodies and did HIV cells “visible” to the immune system.
First, the tests conducted on animals. They have been safely. Then seven volunteers were subjected to experiment. Scientists “caught” in the blood of patients most active immune cells, expand them, entered the back and “unleashed” them on HIV.
The result of the modified cells is well settled in the body of patients without any dangerous side effects. While scientists say that a breakthrough is yet to be seen.
Earlier it was reported that the staff of the University hospital Zurich (Switzerland) conducted an extensive study and identified antibodies that help fight human immunodeficiency virus (HIV).