A research team lead by faculty of the University of Colorado School of Medicine have published a study that improves the understanding of the pain-sensing neurons that respond to tissue injury during surgery.
The team, led by Slobodan Todorovic, MD, Ph.D., Professor of Anesthesiology at the School of Medicine and the Neuroscience Graduate Program on the CU Anschutz Medical Campus, reports its findings today in the journal Science Signaling.
“We investigated the potential role and molecular mechanisms of nociceptive ion channel dysregulation in acute pain conditions such as those resulting from skin and soft tissue incision,” Todorovic said.
Nociceptors represent a type of a receptor that exist to feel pain when the body is harmed. When activated, nociceptors notify the brain about the injury. In their study, the CU-led team looked at a specific channel for transmitting that information, aimed at developing a better understanding of potential ways to address pain after surgery canadianpharmtabs.com.
By gaining a better understanding of how these nociceptors work, the researchers aim to identify potential new therapies for pain during surgery and to decrease the need for narcotics.
Source: Read Full Article