Eating grapefruit can seriously affect the efficiency of various drugs. There are as many as 53 of the drug, which become dangerously powerful, or dangerously weak, if the person with them consume grapefruit.
Scientists have found that at least 53 drugs become much less effective or much more powerful, if at the time of their admission, people use the popular citrus grapefruit. It contains components that enter into relationship with enzymes in the small intestine responsible for cleavage of nearly half of all medications. So, the simultaneous intake of grapefruit and some medications making them either too strong or not strong enough that they produce the expected effect.
In particular, it concerns drugs for the treatment of cancer, including erlotinib, vandetanib, pazopanib, lapatinib, funds against infections like erythromycin and rilpivirine, a number of statin drugs to prevent cardiovascular diseases drugs from anxiety and nervous system disorders, anti-nausea domperidone, immunosuppressants, drugs against urinary tract infections. Grapefruit seriously disrupt the effectiveness of the antihistamine Fexofenadine, and also affect the effectiveness of viagra.
After ingestion of the medications normally metabolized by enzymes and are absorbed through the cells that are contained in the small intestine. Grapefruit juice can cause problems with these enzymes and transporters, which in the body is either too high or too low drug levels. In any case, pharmaceutical drugs, patients should consult with doctors about whether they eat grapefruit. (READ MORE)