American biologists from the medical school of the University of Pennsylvania in Philadelphia was able to establish that the skin of living organisms is able, paradoxically, to improve their functions with the onset of old age. Their finding helps to understand why damaged skin to heal in older people with fewer scars compared to the young, writes the journal Cell Reports.
The researchers experimented with mice and found that blood of young mice is characterized by a content of a large number of special signaling molecules, known as SDF1. This protein substance, as it turned out, is missing in the body of older individuals. Scientists have established that the absence of SDF1 in older rodents is associated with changes in the shell structure of the DNA responsible for the synthesis of the protein.
According to lead author of the scientific work of doctor of medicine Thomas Leung, dermatologists and plastic surgeons are constantly faced with the fact that wounds of the elderly heal with a thinner scar compared to younger patients – however, it was unclear why. Scientist said: in terms of skin aging improves skin ability to heal.
“In youth, our body releases more of SDF1 in the bloodstream to form a scar. With aging we lose this ability, and this allows the tissue to recover,” commented Leung the cause of improving the skin to age.
Scientific experts believe that such “behavior” of the skin due to evolution. In his youth, when injured the body thing to survive, therefore, includes a mechanism that provides the fastest possible delay damages on the skin. In obedience to this biological principle, the skin cells are produced as much as possible, – as a result of the large number of forms scar tissue. In old age a similar process of treatment is more quality – before the body won’t be challenged to live for many more years and to leave offspring.
Earlier Magicforum wrote about that, in which month most often born long-lived.