Multiple sclerosis is a severe autoimmune disease that affects the sheath of nerve fibers in the brain and spinal cord. Scientists from Switzerland have found evidence that the intestinal microflora has a major impact on the immune system and may thereby play a fatal role in the development of this disease.
Specialists of the University of Zurich priority program of clinical research on multiple sclerosis is shared by received data about the nature of the disease in a publication in the journal Science Translational Medicine. In particular, the researchers found that those responsible for the pathological processes of immune cells “are activated in the gut, and then migrate to the brain where they cause an inflammatory cascade”.
Activation of the cells, the researchers found, causes the effect of protein GDP-L-fucosamine formed in bacteria found in the gastrointestinal flora. Scientists believe that their discovery about the influence of the intestinal microbiome on the increased risk of development of dangerous diseases of the CNS should be involved in his therapy. In particular, the method of treatment may be aimed at autoreactive pathological immune cells.
“Gut microbiota can play a much greater role in disease pathogenesis than previously thought,” said the authors of the project.
Earlier Magicforum wrote about the fact that scientists podtverjdaet herpes to penetrate into the brain and provoke the development of fatal disease.