Trial examines how mindfulness meditation may improve mood

In a randomized controlled trial of 134 mildly stressed, middle-aged to older adults, participants who were assigned to a six-week mindfulness-meditation training program experienced significantly reduced negative affect variability—which refers to subjective distress and includes a range of mood states such as worry, anxiety, anger, self-criticism, and life dissatisfaction—compared with participants assigned to a waitlist control.

The effects seen in the Stress & Health study were mediated by a reduction in perceived stress.

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