Following surgery, some patients experience a broken bone around the implants of a total hip replacement—called a periprosthetic femoral fracture. In a study of such patients published in the Journal of Bone and Mineral Research, investigators found that 8.3% of patients had atypical femoral fractures, which are a rare type of femoral stress fracture. The researchers also found a strong association between use of bisphosphonates and risk of atypical femoral fractures.
Previous studies have linked bisphosphonates use to atypical femoral fractures in patients with osteoporosis. However, these are very rare events, which are overwhelmed by the fracture prevention effect of bisphosphonates.
Source: Read Full Article