Found a probiotic that can destroy of antibiotic-resistant bacteria

Infection caused by the bacterium Staphylococcus aureus is the cause of health problems, including sepsis. Strains of this bacterium are resistant to antibiotics, therefore, especially dangerous. However, the researchers found that the probiotic bacteria are able to destroy Staphylococcus aureus.

Methicillinresistant Staphylococcus aureus (MRSA) is highly resistant to treatment with antibiotics, including oxacillin, Flucloxacillin and dicloxacillin. In 2005 in the USA found that 53% of S. aureus isolates resistant to antibiotics. For this reason, scientists are trying sitipokeronline of this bacterium in infected people.

A new study by scientists from the National Institute of Allergy and infectious diseases USA (NIAID) with colleagues from Thailand gives a new hope for healing. Their research convinced that the probiotic bacteriaBacillus is able to fight and effectively eliminate Staphylococcus aureus. The Director of NIAID Dr. Anthony S. Fauci explains the importance of the opening:

Probiotics are often recommended to improve digestion. Our study was one of the first, which accurately describes how certain probiotics can resolve health problems. We assume, that oral Bacillus can be an effective alternative to antibiotic therapy for the treatment of certain conditions.

The effectiveness of Bacillus strains


In the new study, whose results were published in the journal Nature, the researchers worked with 200 participants from rural areas of Thailand. First, the scientists collected and analyzed samples of feces of each participant to try to determine which populations of bacteria can be associated with the absence of S. aureus. It is, in their opinion, helped them to identify the bacteria which stop the spread of Staphylococcus aureus.

They saw that the 101 stool sample contained the probiotic Bacillus, in particular Bacillus subtilis. These bacteria survive well in harsh conditions, and they can be used in the form of greens and vegetables. In addition, together with other beneficial bacteria, they are found in several probiotic products.

When the researchers collected more samples from the intestines, and nose, and checked them for the presence of S. aureus, they noted that the samples containing the Bacillus, did not have S. aureus, and Vice versa. The scientists also conducted some experiments on mice which showed that the bacteria S. aureus have a specialized system that allows them to colonize and grow. However, all the isolates of Bacillus, which scientists have obtained samples from human faeces, were able to effectively inhibit this specialized system.

Using methods that allow them to analyze the components and activity of bacteria, scientists have discovered that the bacilli inhibit specialized system of Staphylococcus aureus, producing molecules called fungicide. In addition, they noticed that fungicide inhibited growth of many strains of S. aureus, including USA300 MRSA, MONUA superbacteria, which is responsible for the most severe infections.

Encouraging results of experiments on mice

In further experiments on mice, scientists injected S. aureus in the intestine of rodents and allow the bacteria to colonize the environment. Then they fed the mice with spores of B. subtilis. The rodents that received disputes once a day, soon got rid of S. aigai. However, this effect was not observed in mice that were fed Bacillus, which had prevented the production of fungicide.



In the future, scientists plan to conduct more experiments to find out whether probiotic products that contain only B. subtilis, to destroy the infection caused by Staphylococcus aureus, the people.

Ultimately, we hope to determine whether you can only use probiotics to reduce infection levels of MRSA in hospitals.

Source: scientific журналNature